Schnitzer is the Director of PRISM since July 2009. Prior to PRISM, he was Professor of Molecular and Cellular Biology at the Sidney Kimmel Cancer Center (1999-2009), where his laboratory received grant support (>$55 million) from NCI, NHLBI, DOD, and California state agencies (TRDRP and CBCRP). Prior to SKCC in 1999, He was an Associate Professor of Pathology at Harvard Medical School and the Beth Israel Deaconess Medical Center in Boston, Massachusetts. From 1990 to 1994, he was an Assistant Professor of Pathology and Medicine at the University of California San Diego School of Medicine and Institute of Biomedical Engineering. He received a BSE in Chemical Engineering from Princeton University and from the University of Pittsburgh Medical School.
He did his postdoctoral training at Yale University School of Medicine in the Department of Cell Biology under the mentorship of the Nobel laureate he has received many awards including the Established Investigator Award from the American Heart Association, the CaP Cure Award in Cancer, and the Kleinerman Lectureship Award for Pulmonary Pathobiology. Over the last decade, he has served as an Associate Editor of several journals and on the Scientific Advisory Board of several companies. He regularly reviews manuscripts for more than 15 journals including Science, Nature, Nature Biotechnology, Nature Cell Biology, Cancer Cell and Nature Medicine. He has served on several NIH study sections for R01 and R21/33 grants as well as program projects and basic/comprehensive cancer centers. He serves on the Board of US-HUPO and recently was elected to a 3 year term as Council Member for the International Human Proteome Organization (HUPO).

Schnitzer has been studying protein interactions at the surface of endothelial cells lining blood vessels and how specialized membrane vesicles called caveolae function to transport endogenous molecules as well as possibly targeted drugs, nanoparticles and gene vectors from the circulatory blood across the endothelial cell barrier to reach underlying tissue and even tumor cells.

Junkang Feng BSc, MPhil, PhD was born in Shanghai China and studied at the Shanghai High School in Shanghai and then graduated from the Institute of Military Engineering of the People’s Liberation Army (PLA), the Chinese armed forces, majoring in Guided Missiles Engineering. In China, he lectured at the National University of Defence Technology of the PLA and then worked as a Research Engineer in a research institute of the Shanghai Academy of Spaceflight Technology. In the UK, he received his MPhil from the University of Portsmouth and PhD from the University of the West of Scotland (the UWS) both in Computer Science. He was a Research Associate in the Department of Computer Science at the University of Manchester before he became a Lecturer and then Senior Lecturer at the UWS. He currently is also the Director of Studies of the Database Research Group of the UWS.

His research interests include qualitative information and information flow theories, distributed information systems and database theory and systems.

K.W. Michael Siu is distinguished Research Professor and NSERC / AB SCIEX Senior Industrial Research Chair in Analytical Mass Spectrometry at York University. He is the Founding Director of York’s Centre for Research in Mass Spectrometry. A major goal of the Centre is to foster collaborative research among academics and with industries in the rapidly expanding field of mass spectrometry. Siu also serves as Associate Vice-President Research, Science and Technology.
Siu has received many awards and honors. Recent accolades include the following: In 2002, the Federation of Chinese Canadian Professionals Education Foundation honoured Siu with the Award of Merit for his long-term impact and exceptional achievement in science. In 2004, Siu received the Gerhard Herzberg Award from the Canadian Society for Analytical Sciences and Spectroscopy for achievement in the science of spectroscopy. In December, 2005, he received the F.P. Lossing Award for significant achievement in Mass Spectrometry from the Canadian Society for Mass Spectrometry. Siu received the 2006 Maxxam Award for significant contributions in analytical chemistry from the Canadian Society for Chemistry in May 2006. In March 2007, Siu received the New Pioneers Award in Science and Technology for his contributions as an immigrant from Skills for Change. Siu received a distinguished Research Professorship from York University at 2007 and was elected as Fellow of the Royal Society of Canada in 2009. Siu has published over 210 scientific papers and 7 peer-reviewed book chapters, co-edited two books, and given over 410 presentations, of which over 60% were invited, keynote or plenary.

K.W. Michael Siu\'s research interests are Fundamentals in Mass Spectrometry, Next-Generation Mass-Spectrometric Hardware Development, Proteomics and Cancer Biomarker Discovery and Quantification.

Edward A. Dennis is Distinguished Professor of Chemistry and Biochemistry and of Pharmacology in the School of Medicine at the University of California at San Diego (UCSD). He received his BA from Yale University in 1963 and a Ph.D. from Harvard University in 1967, a Doctorate in Medicine (honorary) from Goethe University in Frankfurt in 2008, and he served as a Research Fellow at Harvard Medical School.

Lipid Second Messengers and Phospholipases, Characterization of Phospholipase A2, Inhibitors and Cellular Studies, Membrane Phenomenon and Surface Dilution Kinetics, Other Novel Enzymes and Oxidized Lipids

Suphioglu graduated with PhD from the University of Melbourne in 1994 and has over 18 years of research experience (h-index: 22) and an International recognition on the (i) molecular and environmental analysis of pollen, latex and nut allergens, (ii) molecular analysis of phosphoinositide 3-kinase (PI3-K) isoforms in cardiovascular disease and (iii) importance of omega-3 fatty acids and zinc in human neuronal cell survival and epigenetics. Suphioglu has more than 76 publications and several patents. He is currently the Associate Head of School (Development), Course Leader of Bachelor of Biomedical Science and Head of the NeuroAllergy Research Laboratory (NARL).

His research interests are pollen and nut allergy: molecular analysis and novel intervention strategies, grass pollen triggered thunderstorm asthma and importance of omega-3 fatty acids in brain cell survival.

Jorg D. Hoheisel is Head of the Division of Functional Genome Analysis and Chairman of the Scientific Council at the Deutsches Krebsforschungszentrum (DKFZ; German Cancer Research Center) in Heidelberg, Germany. Apart from publishing more than 300 scientific papers, the division filed 47 patents. Jorg Hoheisel is co-founder of four companies; another three companies were set-up by former group members. Prior to joining DKFZ, Jorg Hoheisel worked for five years at the Imperial Cancer Research Fund in London, UK, the initial two years funded by an EMBO fellowship. Before, he had obtained his PhD at the University of Constance, Germany.

Structure, organisation and function of DNA and proteins; bio-molecular methods.

Daoud is the Principal Investigator of the project designed on the title the goal of the proposed research is to define the epigenetic signatures of HCV disease progression to an early stage of HCC in clinical samples obtained from Egyptian patients using an integrated approach of DNA methylation and CGH array technologies. The epigenetic/genetic signatures of the identified targets could then be used as markers for prognosis and diagnosis of the disease as well as targets for new and innovative approaches to the prevention and treatment of HCC especially that a prophylactic vaccine for HCV infection is not yet available. His administrative experience as the PI of two previously funded grants in the similar areas of research SG Komen and DoD as well as his tenure as Associate Professor of Pharmacology attest to his ability to meet the administrative needs of the proposed project. His memberships in the Center for Integrated Biotechnology CIB assure that the assembled team will have access to a wide range of expanding resources. He is also the editor of a newly published book in an area relevant to the proposed research titled “Cancer Proteomics: From Bench to Bedside” by Humana Press 2008.

Daoud research program is in Cancer Therapeutics with major emphasis on integrating Genomics and Proteomics in the Molecular Pharmacology of Cancer.

Kuruc is a serial entrepreneur, starting as a co-founder of Affinity Technology Inc., where he was President from 1990 until 1996 . After it was acquired by LigoTech, Inc., he held an executive business development role until becoming a co-founder of ProFACT Proteomics in 2004. From 1987 to 1990 he held various marketing and sales positions with Amicon Division of W. R. Grace & Co. (now Millipore), and prior to that, product and sales positions with industrial separations equipment suppliers.

Proteomics and Biomarker Discovery.

Natarajan is a lead scientist at USDA-ARS, Beltsville, MD on a risk assessment program and assessing the biosafety of genetically modified soybeans by applying proteomic tools. She is also an Adjunct Associate professor at University of Maryland (College Park, MD). Dr. Natarajan’s research has been recognized by a senior specialist Fulbright grant and a Best Scientist of the year award from the Maryland Governor, Martin O’Malley, in 2008. In addition, she received USDA Administrator’s Outreach, Diversity, and Equal Opportunity (ODEO) awards in 2009 and 2010. She was invited to present her research findings all over the world including Brazil, Egypt, France, India and China. She has a Ph.D. in Botany and two Masters Degrees in Biology.

Proteomics.

He completed his Ph.D in 1977 from California Institute of Technology. From September 1980 – present he is working as Assistant, Associate, and Full Professor of Electrical Engineering and, by courtesy, in the Applied Physics and Aeronautics and Astronautics Departments of Stanford University. He is a Co-founder, Chairman, Senvid, Inc. from October 1999-present and he was Instructor in Applied Physics and Senior Research fellow at Caltech from October 1977 - October 1980. He was the Founder, Chairman, CEO and CTO of Siros Technologies, Inc. From March 1994 - May 2002 and he was a Principal Investigator of DARPA funded $53M Industry Consortium for the development of Digital Holographic Data Storage from April 1994 - April 2000, He is a Member of Royal Dutch Academy of Arts and Sciences Elected Fellow of SPIE, OSA Fulbright scholar Josephine de Karman Fellow Teacher of the year 1983 in Northern CA.

His research interests are encompasses nano-photonics, ultra high density optical data storage, nonlinear optics, optical super-resolution, materials science, three-dimensional image processing and graphics, and internet technologies.

Roman A. Zubarev is a professor of Medical Proteomics in the Department of Medical Biochemistry and Biophysics at the Karolinska Institutet. His research focuses on mass spectrometry. He is known mainly for the development of the fragmentation technique of electron-capture dissociation with Neil Kelleher while in Fred McLafferty\\\'s lab at Cornell University.

His research interests are Mass Spectrometry and Electron-capture dissociation.

Zhenyu Jia is the Biostatistician in Department of Pathology & Laboratory Medicine, University of California Irvine, USA. He earned his PhD at University of California Riverside, USA. He has published 16 Reviewed papers. He has a teaching experience of more than 5 years. He was one of the members in American Statistical Association, American Association for Cancer Research, Pervasive Adaption, and American Society of Human Genetics. He served as a reviewer of 18 peer reviewed journals in the areas of Bioinformatics, Biostatistics and Cancer. He served as Program committee for two conferences.

Zhenyu Jia is particularly interested in development of statistical models for biological data analyses, such as microarray data analysis and genetic mapping. Currently, he works with Strategic Partners for the Evaluation of Predictive Signatures (SPECS) Program on prostate cancer research. They are now aiming to identify expression signatures that are correlated with aggressive prostate cancer and develop a new test that predicts the likely outcome of patients disease based on expression data that is available at the time of their diagnosis.

Suresh Mathivanan is Laboratory Head in La Trobe University, Melbourne, Australia. After successfully completing a Masters degree in Biotechnology, a scholarship from the Department of Biotechnology allowed him to pursue an Advance Post Graduate Diploma in Bioinformatics at the Center for Excellence in Bioinformatics, Pondicherry University, India in 2004. He undertook a Ph.D. at the Johns Hopkins University, USA and Institute of Bioinformatics, India under the guidance of Dr. Akhilesh Pandey. During his doctoral studies, he worked on the Integration of Human Proteomic and Genomic Data using distributed annotation system - named as the Human Protein pedia. After gaining expertise in proteomics and bioinformatics, he joined Prof. Richard Simpson’s group as a postdoctoral researcher in 2008 at the Ludwig Institute for Cancer Research, Melbourne. He received a NH & MRC Biomedical Research Fellowship in 2011 to study exosomes secreted by colorectal cancer cells. He moved to the Department of Biochemistry at the La Trobe University to set up his own research group in 2011.

Suresh Mathivanan research interests are Colorectal cancer, Exosomes, Secretome, Bioinformatics and Microvesicles.

Anthony Addlagatta obtained his bachelors degree with specialisation in industrial chemistry from Osmania University, Masters and the R&D degrees in Chemistry from the School of Chemistry, University of Hyderabad. He worked as a senior scientist at the Pacific Northwest National Laboratory, USA before joining IICT. As a postdoctoral fellow he pursued his research in the area of protein crystallography with Prof. Mariusz Jaskolski (Polish Academy of Sciences, Poznan, Poland), Dr. William L. Duax (Hauptman-Woodward Medical Research Institute, Buffalo, NY) and Prof. Brian Matthews (Howard Hughes Medical Institute, University of Oregon, and Eugene, OR). His work was focused on structural biology of drug targets and structure based drug discovery. He was awarded with Mianowski international fellowship from the Polish Academy of Sciences, Poland and Ramanujan Fellowship by the Department of Science and Technology, New Delhi. He has published 32 research articles and a book chapter.

His current research interests include biochemical and structural characterization of drug target proteins, structure based drug discovery and protein engineering.

Kobeissy is an Assistant Professor at the Department of Psychiatry College of Medicine, University of Florida Gainesville Florida. Kobeissy graduated from the American University of Beirut with a Master′s degree in Immunology. He has also a Master′s in Molecular Genetics with distinction from Bowling Green State University Ohio. He obtained his PhD from the University of Florida in the area of Neuroscience. He joined the Department of psychiatry as the associate Scientific Director of the Neuroproteomics Bioanalytical Laboratory of the Center for Neuroproteomics and Biomarkers Research CNBR, where he expanded neuroproteomics efforts into additional neurological disorders and drug abuse conditions.
He served as a reviewer of peerreviewed journals in the area of proteomics psychiatry and biochemistry. He is on the editorial board of a number of proteomics and systems biology journals. He has published over than 23 reviewed papers in the areas of proteomics and systems biology.He is the author of 8 book chapters and the editor on one book a Psychiatric disorders: Methods and Protocols; 2011 along with three patents in the area of traumatic brain injury. He is the recipient of the distinguished Robinson Neuroscience Research grants for the 2006 and 2007.

His current research focuses on the area of neuroscience and psychiatry with a major interest in drug abuse neurotoxicity and traumatic brain injury neuroproteomics biomarkers. Understanding the underlying molecular mechanisms involved in acute and chronic models of drug abuse paradigms especially in the area of methamphetamine abuse and other associated brain injury including traumatic and ischemic brain injury. High through put analysis of omics data using advanced systems biology approaches that can highlight mechanisms-related to neuronal cell death dynamics as well as looking for therapeutics.

Mingyi Chen ia  a hematopathologist with extensive laboratory background in molecular and cell biology. As a physician scientist, he has devoted his career largely to biomedical research toward malignant hematologic disease. His long-term research goals are to define the molecular pathogenesis of lymphoma/leukemia. Thus, his laboratory primarily focuses on both the genetic and epigenetic alterations of endothelial cells and hematopoietic cells, with each project guided by methods intended to elucidate basic principles as well as practical solutions. Lymphoma/leukemia and other hematological problems are the primary diseases against which advancements in his laboratory are targeted, but the goal is to provide insights that will be applicable to a number of other cancer types and metabolic/degenerative disorders. Through cutting-edge technologies and broadly collaborative approaches, he is also committed to build a strong, unique and competitive research program that will ultimately benefit patients.

Qiangwei Xia has received a PhD in Molecular and Cellular Biology from the University of Washington in 2007. Due to his significant impact on the field of quantitative proteomics, Dr. Xia received the 2006 China National Award, the Chinese government�s highest level postgraduate education award. Throughout an impressive nine (9) year research career, Xia has been working in the field of mass spectrometry-based proteomics. He has made distinct contributions in mass spectrometry instrumentation, bioinformatics, microbial biology research, human oral pathogen research, cancer research, neurodegenerative disease research, biomarker discovery, and stem cell research. He Xia is the author of eighteen (18) peer-reviewed articles. He serves as a reviewer for Analytical Chemistry, Journal of Proteomics, and BioTechniques. In his upcoming position at Regeneron Pharmaceuticals, Xia will be leading studies performed in the Analytical Biochemistry Group to characterize therapeutic proteins using cutting-edge mass spectrometry techniques.

Quantitative Proteomics, Protein De novo Sequencing, Protein Post-translational and In-process Modifications, Mass Spectrometry Instrumentation, Bioinformatics Software Development, Peptide Fragmentation Technology, Protein/Peptide Biomarker Discovery and Protein Structural Characterization.

Uday Kishore carried out his PhD research from Delhi University, India and post-doctoral training at the Salk Institute, California and the University of Oxford, UK. He has been the recipient of fellowships/awards from the NASA, Wellcome Trust, Humboldt Foundation, Medical Research Council and European Commission. He has authored over 80 peer-reviewed research papers, 10 book chapters, 2 International patents, edited two books, and is currently writing a text book on host-pathogen interaction (Wiley-Blackwell). His research interests include understanding the roles of innate immunity (including complement system) in allergy, host-pathogen interaction, pregnancy, neuroinflammation and neurodegeneration, and autoimmunity.

1. Mechanisms underlying therapeutic effects of exogenous recombinant surfactant protein D (SP-D) in disease models of pulmonary hypersensitivity, inflammation and infection
2. Host pathogen interaction studies using models such as Aspergillus fumigates, Mycobacterium tuberculosis, malaria parasite and Schistosomes.
3. In vivo modulation of dendritic cell functions and mechanism of helper T cell polarisation by SP-D
4. Mechanisms governing SP-D mediated survival and induction of apoptosis of eosinophils and macrophages
5. Instructive role of collectins and complement proteins in dendritic cell-mediated handling of apoptotic cells etc.,

Hany A. El-Shemy received his two Ph.D. degrees in biochemistry and genetic engineering from the University of Cairo, Egypt and Hiroshima University, Japan. He became an Assistant Professor with Biochemistry Department of Cairo University, Egypt from Sept, 1996, and advanced to Associate Professor in Sept, 2002, as well as full professor in March 2007. His research interests are in the fields of plant biotechnology and medicinal plants. He received 2 patents, wrote 2 book chapters, published more than 60 SCI Journal papers, and 25 conference presentation, and served as the technique committee member as well as chair in many International conferences and the editors including PLoS ONE, BMC Genomics, CIMB journals, also reviewer for more than 10 SCI cited journals. He received several awards, including State prize Award from Academy of Science, Egypt (2004), Young Arab Researcher prize Awarded from Shuman Foundation, Jordan (2005).

Hany A. El-Shemy research interests includes Functional Genomics of R genes and Metabolomics Techniques, Prepare reports, Manuscripts and Presentation.

Xiang-Jia Min is Assistant Professor in the Center for Applied Chemical Biology, Youngstown State University, USA. He received his Master degree in Software Systems from University of British Columbia in 2002 and his PhD in Plant Science from University of Hawaii in 1995. He is serving on the Ohio Plant Biotechnology Consortium as the YSU representative.  He is an editorial board member of the Journal of Proteomics and Bioinformatics and a reviewer for the following journals:  Bioinformatics; Journal of Proteomics & Bioinformatics; Nucleic Acids Research; Molecular Biology and Evolution; Folia Microbiologica.  He has published 25 papers in journals and books. He implemented some widely used software tools including ORF Predictor, Tarnget Identifier and AS Finder.

Xiang-Jia Min research interests are Bioinformatics software and database development - software tools for DNA seqeunce analysis, ORF prediction, identification of alternatively spliced genes, data mining; knowledge database development for secretomes; Gene and genome annotation and evolutionary analysis.

Jiaxu Li is an Associate Professor in the Department of Biochemistry and Molecular Biology at Mississippi State University. He received his Doctorate of Philosophy from the Pennsylvania State University where he worked in the laboratory of Dr. Sarah Assmann on protein kinase mediated signaling pathways in plant guard cells. He did his postdoctoral research in the laboratory of Dr. Steven Gygi at Harvard Medical School studying protein interaction quantification and post-translational modifications in yeast using mass spectrometry based proteomic approaches.

Jiaxu Li current research focuses on histone lysine methylation in epigenetic regulation of plant development and abscisic acid-dependent phosphorylation in plant responses to environmental stress.

R. Nageswara Rao is a Chief Scientist working in Analytical Chemistry Division of Indian Institute of Chemical Technology, Hyderabad. He obtained his Ph.D in chemistry from Osmania University, Hyderabad, has more than 34 years of research association with various R&D projects of IICT in development of chromatographic, spectroscopic and computer-assisted analytical methods for process development and quality assurance of drugs & pharmaceuticals, agrochemicals, petrochemicals and fine chemicals which includes generation of analytical data for drug master files for registration purposes. He has published about 150 research papers, which include two book chapters, ten review articles and presented more than 75 papers in National and International seminars/symposia. Visited the Universities of Amsterdam, Netherlands (1998), Jena, Germany (2005), Washington, USA (2009) and Daejeon, South Korea (2010). He is a member of professional bodies viz., President(2008-2011), secretary (1994-1999) & Life Member of ISAS Hyderabad Chapter, Life Member of OTAI, Southern Zone, Hyderabad, member of technical committees viz., CFE, AP Pollution Control Board, Task Force Pharma Education in AP, PEMC,CCRUM, New Delhi and BIS, New-Delhi. He is a recognised guide for supervising the research work of Ph.D students of various Universities. Ten of his students were awarded Ph.D and 12 are working at present. He has received several honours and awards which include IDMA Research Award (1987), ISAS Best Paper Presentation Award (1993), IICT Annual Day Awards for Publications (1990, 1992, and 1994), Dr. Husain Zaheer Memorial Award (1997), IDMA Outstanding Pharmaceutical Analyst Award (2004), German Academic Exchange (DAAD) Fellowship (2005); Marquis Who’s who in the World (2006) and Brain Pool Fellowship (2010).

His research interests are development of chromatographic, spectroscopic and computer-assisted analytical methods for process development and quality assurance of drugs & pharmaceuticals, agrochemicals, petrochemicals and fine chemicals which includes generation analytical data for drug master files for registration purposes

Hesham H. Ali is a Professor of Computer Science and the Lee and Wilma Seaman Distinguished Dean of the College of Information Science and Technology (IS&T), at the University of Nebraska at Omaha (UNO). He is also the director of UNO Bioinformatics Core Facility that supports a large number of biomedical research projects in Nebraska. He has published numerous articles in various IT areas including scheduling, distributed systems, wireless networks, and Bioinformatics. He has also published two books in scheduling and graph algorithms, and several book chapters in Bioinformatics. He is currently serving as the PI or Co-PI of several projects funded by NSF, NIH and Nebraska Research Initiative (NRI) in the areas of wireless networks and Bioinformatics. He has been leading a Bioinformatics Research Group at UNO that focuses on developing innovative computational approaches to identify and classify biological organisms. The research group is currently developing new graph theoretic models for assembling short reads obtained from high throughput instruments, as well as employing a novel correlation networks approach for integrating and analyzing large heterogeneous biological data associated with various biomedical research areas. He has also been leading two funded projects for developing secure wireless infrastructure and using wireless technologies to study mobility profiling for aging research.

Current research interests include the areas of Bioinformatics, Wireless Networks, Graph Modeling, Design and Analysis of Algorithms, mobile computing and scheduling.

Sompop Bencharit is an Assistant Professor in the Department of Prosthodontics School of Dentistry and an Adjunct Assistant Professor in the Department of Pharmacology, School of Medicine at the University of North Carolina at Chapel Hill UNC. Bencharit received his DDS in 1994 and Clinical Diploma in Prosthodontics in 1996 from Chulalongkorn University Bangkok, Thailand. Bencharit came to UNC in 1996 for his residency training and graduate education. He earned his Certificate and Master Degree in Prosthodontics in 1999 a PhD in Oral Biology in 2003 and a Certificate in Clinical Research in 2008 from UNC. In November 2009, Bencharit became a Diplomate of the American Board of Prosthodontics and a Fellow of the American College of Prosthodontists. He is one of the very few clinician scientist who is both board certified dental specialists and PhD scientists.

Bencharit is a protein structural biologist specializing in protein X-ray crystallography. He has his research interests in structural biology and its applications to human diseases in particular the role of signaling proteins involved in vessel and bone development. He is also interested in the clinical applications of salivary and tissue proteomics using advanced mass spectrometry. His main laboratory goals include (1) structural and functional studies of cerebral cavernous malformation (CCM), a genetic disorder resulting in vascular defects in the brain causing hemorrhagic stroke (2) salivary proteomic analysis and biomarker discovery for diabetes and HIV-related diseases, and (3) biology of bone regeneration and implant dentistry.